The Kircher Lab studies genetic variant effects throughout the genome. We are developing computational methods to predict the deleteriousness of genetic variants, study the effects of non-coding sequence alterations (e.g. using massively parallel reporter assays and functional read outs) and analyze cell-type contributions of cell-free DNA. We can be found at two locations. We are part of the Institute for Human Genetics of the University of Lübeck (UzL) and the University Medical Center Schleswig Holstein (UKSH), where we are located in the BMF building on the Campus Lübeck. We are also part of the Berlin Institute of Health (BIH), the translational research institute of Charité - Universitätsmedizin Berlin, where we are located at the Charité Campus Mitte.
You are excited about our research topics and want to join the lab? Please reach out.